Exosomes Provide Scientific Basis to Skin Aging Mechanisms
— Pukyong National University research team presents a new paradigm in anti-aging technology
A groundbreaking research finding in skin science has been announced in Korea, drawing significant attention in the industry. The team led by Professor Eom Woo-ram from the Department of Biotechnology at Pukyong National University has scientifically elucidated the mechanism through which stem cell-derived exosomes inhibit skin aging. This research, published in the prestigious journal 'ACS Nano(IF: 15.8)', is recognized for its excellence and is seen as revolutionary in the fields of regenerative medicine and skin aesthetics.
Exosome Induces Fundamental Recovery of Skin Cells
Exosomes are nano-sized vesicles derived from stem cells that are involved in cell-to-cell signal transmission and tissue regeneration. Recently, they have garnered significant attention in anti-aging and skin regeneration fields as bio-derived substances. In this study, Professor Eom’s team systematically analyzed over 210 previous papers both domestically and internationally and scientifically validated that stem cell-derived exosomes exhibit the following biological active functions:
- Promotion of collagen synthesis in the dermal layer of skin
- Inhibition of inflammatory responses
- Reduction of oxidative stress like reactive oxygen species (ROS)
These mechanisms directly target cell damage factors that cause decreased skin elasticity and deep wrinkles, enabling a more fundamental anti-aging effect than existing methods that merely attempt moisturizing or temporary improvements from the outside.
Evolution of Exosome Delivery Technology in Fusion with Medical Devices
Another noteworthy achievement of this study is the presentation of a fusion solution to enhance the delivery efficiency of exosomes. Professor Eom’s team proposed a method that concurrently applies microneedles and hydrogels for effectively delivering exosomes deep into the skin.
Microneedles are medical devices that delicately stimulate the epidermal layer of the skin to facilitate the delivery of exosomes to the dermal layer, while hydrogels, in gel form containing moisture, adhere to the skin, inducing continuous and stable absorption of effective ingredients. This system ensures that exosomes are not easily damaged in external environments and can directly engage in restoring physiological functions within the skin.
The Next Generation in the Cosmetics Industry: Necessity of Science-Based Functional Approach
The domestic cosmetics industry is experiencing a steady surge in demand for high-functionality products due to the aging society and increased interest in beauty. Within this trend, the scientifically-based skin regeneration technology proposed by exosomes is evolving into a regenerative medical solution aimed at improving skin disorders, surpassing mere ‘functionality’.
Such transformation will be a critical key in strengthening clinical approval standards and securing user trust in the future, highlighting the growing importance of obtaining scientifically validated data and establishing a technological application platform.
YURICO5’s Perspective: Focus on Science-Based Skin Solutions
These research outcomes align with our company’s direction in technology development. YURICO5 has been focusing on utilizing scientifically verified ingredients proven for their safety and efficacy, solidifying our position in the skin protection realm with specialized full-spectrum UV and blue light blocking technology. Looking ahead, we intend to scientifically design various functions necessary for preventing skin aging, such as restoring skin barriers and alleviating oxidative stress.
Furthermore, YURICO5 plans to deeply consider the incorporation and formulation of exosome-related technologies in cosmetics application, given clear validation of the technology's skin compatibility, safety, and efficacy degradation mechanism, in compliance with regulatory levels and quality standards.
In Conclusion
The study by Professor Eom Woo-ram’s team from Pukyong National University has not only proven the efficacy of exosomes in preventing skin aging but also holds significant meaning by indicating the future direction of evidence-based development in the anti-aging and skin regeneration sectors. Only by continuously investing in and researching ingredients and technologies whose action mechanisms are scientifically proven, not just following trends, can the future of the cosmetic industry, genuinely restoring users' skin health, be opened.
Emphasizing essential skin protection grounded in complete UV and blue light blocking technology, YURICO5 commits to carrying forward with responsible innovation.
This research by Professor Eom Woo-ram’s team is recognized as a significant advancement, seeking intersections between cosmetics and regenerative medicine. YURICO5 is dedicated to developing high-quality cosmetics aimed at restoring fundamental skin health, an initiative supported by such scientific foundations.
